Édouard Kouassi

Appel aux communications ACFAS

Axe de recherche

• Signatures biologique, psychologique et sociale de la maladie mentale 
• Traitement et réadaptation adaptés aux populations 
  

Affiliation universitaire (poste ou fonction)

Professeur - Chercheur agrégé, Faculté de Médecine, Département Médecine et spécialités médicales, Université de Montréal

Profil

• Sérotonine et cellules sanguines
• Médicaments et système immunitaire
• Bases moléculaires des relations cerveau-immunité
• Approches écosystémiques de la santé

Prix et distinctions

Chercheur-boursier, programme conjoint du Conseil de recherches médicales du Canada (CRM) et de l’Association Canadienne de l’Industrie du Médicament (ACIM), 1992-1997.

Enseignement

• Pathologie et immunologie générales (MMD 1229)
• Sciences hématologiques (MMD 1231)
• Métabolisme des médicaments (PHL 6081)
• Toxicologie des médicaments (TXL 6012)
• Méthodes analytiques en toxicologie (TXL 6002)

Publications récentes

Koné B., Feagan M., Houenou Y.A., Brou N., Houenou P.V., Fayomi B., Ngnikam E., Cissé G., Spiegel J., Kouassi E. Facilitating the relationship between researchers and policy-makers:  experiences from three Ecohealth projects in West and Central Africa. EcoHealth. In press.

Igue, R., Potvin, S., Bah, R., Stip, E., Bouchard, R. H., Lipp, O., Gendron, A. Kouassi, E. (2011). Soluble interleukin-2 receptor levels correlated with positive symptoms during quetiapine treatment in schizophrenia-spectrum disorders. Progress in neuro-psychopharmacology & biological psychiatry,35(7), 1695-1698. Pubmed

Potvin S., Stip E, Sepehry A.A., Gendron A., Bah R., Kouassi E. Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review. Biological Psychiatry, 63 : 801-808, 2008.

Potvin S., Kouassi E., Lipp O, Bouchard R.H., Roy, M.A., Demers M.F., Gendron A., Astarita G., Piomelli D., Stip E. Endogenous cannabinoids in patients with schizophrenia and substance use disorder during quetiapine therapy Journal of Psychopharmacology 22: 262-269, 2008.

Landau A.M., Kouassi E., Siegrist-Johnstone R., and Desbarats J. Unexpected findings in a proteasome inhibition model of Parkinson’s Disease. Movement Disorders 22: 403-407, 2007.

Landau A.M., Luk K.C., Jones M.L., Siegrist-Johnstone R., Young Y.K., Kouassi E., Rymar V.V., Dagher A., Sadikot A.F., and Desbarats J. Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease. The Journal of Experimental Medicine 202: 575-581, 2005.

Abdouh M., Albert P.R., Drobetsky E., Filep J.G., and Kouassi E. 5-HT1A-mediated promotion of mitogen-activated T and B cell survival and proliferation is associated with increased translocation of NF-kappaB to nucleus. Brain, Behavior, and Immunity, 18 : 24-34, 2004.

Colombo M., Hamelin C., Kouassi E., Fournier M., and Bernier J. Differential effects of mercury, lead, and cadmium on IL-2 production by Jurkat T cells. Clinical Immunology 111: 311-322, 2004.

Gendron A., Kouassi E., Nuara S., Cossette C., D'angelo G., Geadah D., du Souich P., and Teitelbaum J. Transient middle cerebral artery occlusion influence on systemic oxygen homeostasis and erythropoiesis in Wistar rats. Stroke 35: 1979-1984, 2004.

Moisan E., Kouassi E., and Girard D. Mechanisms involved in methylmercuric chloride (MeHgCl)-induced suppression of human neutrophil apoptosis. Human & Experimental Toxicology, 22: 629-637, 2003.

Gendron A., Teitelbaum J., Cossette C., Nuara S., Dumont M., du Souich P., Geadah D., and Kouassi E. Temporal effects of left versus right middle cerebral artery occlusion on spleen lymphocyte subsets and mitogenic responses in Wistar rats. Brain Research 955: 85-97, 2002.

Moisan E., Arbour S., Nguyen N., Hébert M.J., Girard D., Bernier J., Fournier M., and Kouassi E. Prolongation of human neutrophil survival by low-level mercury via inhibition of spontaneous apoptosis. Journal of Toxicology and Environmental Health, Part A, 65: 183-203, 2002.

Abdouh M., Storring J.M., Riad M., Paquette Y., Albert P.R., Drobetsky E., and Kouassi E. Transcriptional mechanisms for induction of 5-HT1A receptor mRNA and protein in activated B and T lymphocytes. Journal of Biological Chemistry 276: 4382-4388, 2001.