Edouard Kouassi

Research Areas

• Biological, Psychological and Social Signatures of Mental Health
• Treatment and Rehabilitation adapted to Populations
  

University Affiliation (Position or Role)

Associate Professor, Faculty of Medicine, Dept. Medicine and medical specialities, University of Montreal

Profile / Research Interests

• Drugs and the immune system
• Molecular bases of neural-immune interactions
• Serotonin and blood cells
• Ecosystem approaches to health

Awards and Honours

Research Career Award in Health Sciences, Medical Research Council of Canada (MRCC) and Pharmaceutical Manufacturing Association of Canada (PMAC), 1992-1997

Teaching

• General pathology and immunology (MMD 1229)
• Hematological sciences (MMD 1231)
• Drug metabolism (PHL 6081)
• Drug toxicology (TXL 6012)
• Analytical methods in toxicology (TXL 6002)

Recent Publications

Koné B., Feagan M., Houenou Y.A., Brou N., Houenou P.V., Fayomi B., Ngnikam E., Cissé G., Spiegel J., Kouassi E. Facilitating the relationship between researchers and policy-makers:  experiences from three Ecohealth projects in West and Central Africa. EcoHealth. In press

Igue, R., Potvin, S., Bah, R., Stip, E., Bouchard, R. H., Lipp, O., Gendron, A. Kouassi, E. (2011). Soluble interleukin-2 receptor levels correlated with positive symptoms during quetiapine treatment in schizophrenia-spectrum disorders. Progress in neuro-psychopharmacology & biological psychiatry, 35(7), 1695-1698. Pubmed

Potvin S., Stip E, Sepehry A.A., Gendron A., Bah R., Kouassi E. Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review. Biological Psychiatry, 63 : 801-808, 2008.

Potvin S., Kouassi E., Lipp O, Bouchard R.H., Roy, M.A., Demers M.F., Gendron A., Astarita G., Piomelli D., Stip E. Endogenous cannabinoids in patients with schizophrenia and substance use disorder during quetiapine therapy Journal of Psychopharmacology 22: 262-269, 2008.

Landau A.M., Kouassi E., Siegrist-Johnstone R., and Desbarats J. Unexpected findings in a proteasome inhibition model of Parkinson’s Disease. Movement Disorders 22: 403-407, 2007.

Landau A.M., Luk K.C., Jones M.L., Siegrist-Johnstone R., Young Y.K., Kouassi E., Rymar V.V., Dagher A., Sadikot A.F., and Desbarats J. Defective Fas expression exacerbates neurotoxicity in a model of Parkinson's disease. The Journal of Experimental Medicine 202: 575-581, 2005.

Abdouh M., Albert P.R., Drobetsky E., Filep J.G., and Kouassi E. 5-HT1A-mediated promotion of mitogen-activated T and B cell survival and proliferation is associated with increased translocation of NF-kappaB to nucleus. Brain, Behavior, and Immunity, 18 : 24-34, 2004.

Colombo M., Hamelin C., Kouassi E., Fournier M., and Bernier J. Differential effects of mercury, lead, and cadmium on IL-2 production by Jurkat T cells. Clinical Immunology 111: 311-322, 2004.

Gendron A., Kouassi E., Nuara S., Cossette C., D'angelo G., Geadah D., du Souich P., and Teitelbaum J. Transient middle cerebral artery occlusion influence on systemic oxygen homeostasis and erythropoiesis in Wistar rats. Stroke 35: 1979-1984, 2004.

Moisan E., Kouassi E., and Girard D. Mechanisms involved in methylmercuric chloride (MeHgCl)-induced suppression of human neutrophil apoptosis. Human & Experimental Toxicology, 22: 629-637, 2003.

Gendron A., Teitelbaum J., Cossette C., Nuara S., Dumont M., du Souich P., Geadah D., and Kouassi E. Temporal effects of left versus right middle cerebral artery occlusion on spleen lymphocyte subsets and mitogenic responses in Wistar rats. Brain Research 955: 85-97, 2002.

Moisan E., Arbour S., Nguyen N., Hébert M.J., Girard D., Bernier J., Fournier M., and Kouassi E. Prolongation of human neutrophil survival by low-level mercury via inhibition of spontaneous apoptosis. Journal of Toxicology and Environmental Health, Part A, 65: 183-203, 2002.

Abdouh M., Storring J.M., Riad M., Paquette Y., Albert P.R., Drobetsky E., and Kouassi E. Transcriptional mechanisms for induction of 5-HT1A receptor mRNA and protein in activated B and T lymphocytes. Journal of Biological Chemistry 276: 4382-4388, 2001.