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Arseneault-Lapierre, Geneviève, Doctorante, Neurosciences, Université McGill
Fernand-Seguin Research Center
7401, Hochelaga street
Montréal (Québec) H1N 3M5
Phone: 514-251-4000, ext 3256
Email :genevieve.arsenault-lapierre@mail.mcgill.ca
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Research Axis
Neurosciences humaines
Centre d’Études sur le Stress Humain
Supervisors
Dr. Sonia Lupien
Project
Cortisol Secretion in Individuals with Mild Cognitive Impairment
Abstract : Salivary cortisol could be used as a marker of the risk for Alzheimer’s disease, especially in individuals with Mild Cognitive Impairment (MCI). Before we address this issue, however, we have to study the secretion of salivary cortisol in these people. Therefore, this project aims at studying the secretion of salivary cortisol in healthy elderly adults, individuals with MCI and patients with Alzheimer’s disease. We will follow these three groups over two years and measure, in addition to their salivary cortisol levels, their cognition and several brain structures known to be affected in the disease. This will allow us to understand better the complex relationship between cognitive and brain changes and cortisol secretion in individuals with MCI, who are at risk of progressing to dementia.
Publications
Articles
Arsenault-Lapierre, G., Chertkow, H., & Lupien, S. (2008). Seasonal effects on cortisol secretion in normal aging, mild cognitive impairment and Alzheimer's disease. Neurobiol Aging.
Arsenault-Lapierre, G., Kim, C., & Turecki, G. (2004). Psychiatric diagnoses in 3275 suicides: a meta-analysis. BMC Psychiatry, 4, 37.
Abstracts
Arsenault-Lapierre, G., Lupien, S., & Chertkow, H. (2008). Salivary cortisol levels are increased in Mild Cognitive Impairment and Alzheimer Disease compared to normal elderly controls when effects of season are taken into account. Alzheimer's and Dementia: The Journal of the Alzheimer Association, 4(4), T251.
Arsenault-Lapierre, G., Lupien, S., & Chertkow, H. (2008). Salivary cortisol levels are increased in Mild Cognitive Impairment and Alzheimer Disease compared to normal elderly controls when the effects of season are taken into account. The Canadian Journal of Geriatrics, 11(1), 53.
Arsenault-Lapierre, G., Whitehead, V., Belleville, S., Massoud, F., Bergman, H., & Chertkow, H. (2008). Mild Cognitive Impairment subcategories depend on the source of norms. The Canadian Journal of Geriatrics, 11(1), 60.
Arsenault-Lapierre, G., Whitehead, V., Belleville, S., Massoud, F., Bergman, H., & Chertkow, H. (2008). Mild Cognitive Impairment subcategories depend on the source of norms. Alzheimer's and Dementia: The Journal of the Alzheimer Association, 4(4), T260.
Arsenault-Lapierre, G., Whitehead, V., De Sousa, K., Malus, M., & Chertkow, H. (2005). Word reading threshold and Mold Cognitive Impairment. Proceedings of 10th Annual McGill Division of Geriatrics Research Day, 8.